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KMID : 1025520110530010007
Journal of Animal Science and Technology
2011 Volume.53 No. 1 p.7 ~ p.13
Association Study Between the Polymorphisms of Exostosin-1 Gene and Economic Traits in Hanwoo
Kim Bum-Soo

Kim Nam-Kuk
Lee Seung-Hwan
Cho Yong-Min
Heo Kang-Nyeong
Park Eung-Woo
Yang Boo-Keun
Yoon Du-Hak
Abstract
The aim of this study was to identify the polymorphism on exostosin-1(EXT1) gene and to associate with economic traits in Hanwoo(Korean cattle). We sequenced for detection of single nucleotide polymorphism(SNP) with 24 unrelated individuals and identified four SNPs(T272196A, C272359T, G290964A and A302092G). Relationship between the genotypes of 583 Hanwoo individuals by PCR-RFLP and economic traits were analyzed by general linear model. In EXT1 gene, there were four SNPs associated with economic traits such as eye muscle area breeding value, marbling score breeding value, backfat and thickness breeding value(p<0.05 to p<0.01). In conclusion, this study indicates an important role of EXT1 gene in determining the meat quality or economic characteristics in Hanwoo.
KEYWORD
Hanwoo, EXT1, SNP, PCR-RFLP
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